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Hypercalcemia, The most serious potential unwanted effect, Carries a risk of mental impairment, Calcification of soft flesh, Seizures, cardiac arrest, Renal damage and death. Hypercalcemia may not manifest until 1 to 6 months after the lesions resolve.7 Calcium levels should be checked regularly. proper care, if required,red bottoms shoes, is generally with pamidronate (0.5 you can 2.0 mg/kg) and usually done in consultation with pediatric endocrine specialists,
inside of study, We show those, With blending MGDF plus SCF for a total ex vivo culture of 10 days, you're able to obtain a mean 676fold expansion of CD41+ cells from CD34+ cells in clinically suitable conditions. Previous studies from the laboratory have shown that the combination of SCF and MGDF is optimal for the generation of MK in vitro from CD34+ cells in serumfree medium and the inclusion of welldefined lipids.12 Considering these in vitro data and that observed in a baboon model of autologous transplantation in which a significant decrease of the median delay of platelet recovery was observed in a CD34+ expansion study using four cytokines (SCF, TPO, IL3, as LFlt3),3 we tested whether MGDF plus SCF is an optimal formula for ex vivo expansion of MK progenitor cells.Our study displays the safety of ex vivo expanded MK precursor cells reinfused after highdose chemotherapy in patients with relapsed malignant lymphoma. This observation is in concordance with that previously reported in the baboon model of autologous transplantation.3 Among all declared studies, Platelet transfusion support and duration of thrombocytopenia lower than 20 000/l can not be compared because of various highdose chemotherapy regimens and eventual coreinfusion of standard PBPC.
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